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What is Class 1 & class 2 MHC molecule binding?

What is Class 1 & class 2 MHC molecule binding?
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Class 1 MHC binding - MHC class 1 glycoproteins are present on almost every cell in the body. Binds to endogenous antigens synthesized in a cell. These present antigens to cytotoxic T-cells lymphocytes. On the cell surface, the membrane bound MHC 1 protein displays the antigen for recognition by immune cells known as cytotoxic T cell lymphocytes. Presence of foreign antigen targets cell for destruction .

Class 2 MHC binding - MHC 2 glycoproteins are present only on antigen presenting cells . Binds CD4 adhesion molecule on helper T Cells to exogenous proteins. These helper T cells are activated upon binding to macrophage, causing release of lymphokines , attracting other cells , to the infectious area in order to confine and destroy the antigenic material .

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