● Steroid hormone.
• Example.
glucocorticoids
mineralocorticoids
androgens
oestrogens
progestogens.
• The action of steroid hormones
1. The steroid hormone easily cross the cell membrane as well as
the nuclear membrane
2. This then binds to pre-formed steroid receptors in the cytoplasm
or in the nucleoplasm.
3. Binding to steroid hormone receptor lead to conformational
change to the receptor.
4. The hormone-receptor complex binds to the hormone responsive
element of the gene, leading to its transcription and the formation
of proteins
● Peptide Hormone.
• Example.
Calcitonin
Insulin
Glucagon
Oxytoxin
Endorphins
Adrenocorticotropic hormone
Anti-diuretic hormone
• Action :
Peptide hormone interact with specific receptor at the extracellular domain with through transmembrane domain activate the cytosolic domain to release intracellular signals
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