Question

What are steroid and peptide hormones? Explain the difference between the mechanisms of steroid and peptide...

  1. What are steroid and peptide hormones? Explain the difference between the mechanisms of steroid and peptide hormone action.

Homework Answers

Answer #1

● Steroid hormone.

• Example.

glucocorticoids

mineralocorticoids

androgens

oestrogens

progestogens.

• The action of steroid hormones

1. The steroid hormone easily cross the cell membrane as well as the nuclear membrane

2. This then binds to pre-formed steroid receptors in the cytoplasm or in the nucleoplasm.

3. Binding to steroid hormone receptor lead to conformational change to the receptor.

4. The hormone-receptor complex binds to the hormone responsive element of the gene, leading to its transcription and the formation of proteins

● Peptide Hormone.

• Example.

Calcitonin
Insulin
Glucagon
Oxytoxin
Endorphins
Adrenocorticotropic hormone
Anti-diuretic hormone

• Action :

Peptide hormone interact with specific receptor at the extracellular domain with through transmembrane domain activate the cytosolic domain to release intracellular signals

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