Question

Explain the mechanisms by which the liver and kidney retains glucose but eliminate urea. Your explanation...

Explain the mechanisms by which the liver and kidney retains glucose but eliminate urea. Your explanation should outline the structure of these organs and explain how they achieve this function.

Secondly, explain the regulation of blood glucose through negative feedback mechanisms

Science   Anatomy-And-Physiology   
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Answer #1

ANSWER :

The liver converts ammonia (toxic nitrogenous compound) to urea via deamination of amino acids and urea cycle. Urea transports to the kidneys via blood circulation to excrete in urine If present in higher concentrations. But glucose is stored in the liver in the form of glycogen (polysaccharide) via glycogenesis process and does not passes out into urine due its reabsorption in the renal tubules of nephrons of kidney.

Blood glucose is regulated via negative feedback mechanism, when blood glucose level drops down in the body cell which sensed via pancreatic cells then alpha cells of pancreas islets secrete glucagon hormone which converts stored glycogen of liver into glucose via glycogenolysis process and blood glucose level return to its normal range.

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