Question

Jen has suffered from epilepsy since child. Recently, she learned she has mutations in certain genes that control the K⁺ channels in neurons. Her doctor thinks these mutations are related to her epilepsy. How would non-functional or poorly functioning K⁺ channels be causing epileptic events?

Answer 1

Pottasium Chan when it undergoes genetic mutation it will cause the occurrence of epilepsy. This condition is predominantly seen in children

Inward rectifier pottasium Chanel

They's have a great function in the occurrence of epilepsy . In a cell the occurrence of epilepsy is when the resting membrane potential is altered and when alteration astrocytic kir4.1 that is when this mutation occur the resting membranes potential will have rapid firing as ther will be increased exitability of the neuron . This in children and neonates develop epilepsy from childhood onward .