Question

Some types of blood pressure medication work by blocking the effects of aldosterone on the kidneys. What effect would these drugs have on the sodium ion concentration in the blood and how would this effect blood pressure?

Answer 1

Answer

Alsosterone acts on distal part of nephrone in kidney and enchances sodium reabsorption.

• Medication that blocks the effects of aldosterone on the kidneys tend to interfere with the process of sodium reabsorption.
• As a result there will be low sodium concentration in blood.
• Sodium creates a concentration gradient for water to be removed from the body.
• Medications blocks aldosterone to remove more sodium in urine. With sodium, excess water is too removed in the urine.
• By removing excess water, fluid balance in the body is maintained that helps in lowering the blood pressure.