Question

Nervous system functions that directly employ acetylcholine neurotransmitter are referred to as cholinergic. Drugs that might be therapeutic in treating the symptoms of dopamine loss in Parkinson’s disease could include

• dopaminergic antagonists and cholinergic agonists.

• dopaminergic agonists and cholinergic antagonists.

• dopaminergic antagonists and cholinergic antagonists.

• dopaminergic agonists and cholinergic agonists.

2. From the information provided, drugs used to treat Parkinson’s disease symptoms will act at which location?

• The striatum

• The globus pallidus

• The substantia nigra

3. Which of the following might be therapeutic in the treatment of Parkinson’s disease symptoms?

• decreasing dopamine uptake

• increasing dopamine receptor responsiveness

• monoamine oxidase inhibition

• increasing dopamine release

• all of these choices listed may be therapeutic

4. Many neurons with dendrites in the striatum send action potentials to another basal gangliar region called the globus pallidus. These neurons constitute what is known as a __________ pathway.

• striatopallidal

• substantiopallidal

• pallidostriatal

Answer 1

1. Parkinsonism is a progressive degeneratve disorder of the central nervous system which affects movement.

The different class of drugs used to treat parkinsonism include dopaminergic agonists, cholinergic antagonists, Monoamine oxidase - B inhibitors.

Drugs that might be therapeutic in treating the symptoms of dopamine loss in Parkinson’s disease could include dopaminergic agonists and cholinergic antagonists.

2. Drugs used to treat Parkinson’s disease symptoms will act at the striatum

3. Monoamine oxidase inhibition is therapeutic in the treatment of Parkinson’s disease symptoms.

4. Many neurons with dendrites in the striatum send action potentials to another basal gangliar region called the globus pallidus. These neurons constitute what is known as a striatopallidal pathway.