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Write a paragraph on the mechanism of Adrenocorticostropic hormone (ACTH). Using the following passway: Hypothalamus—> CRH—>...

Write a paragraph on the mechanism of Adrenocorticostropic hormone (ACTH).
Using the following passway:
Hypothalamus—> CRH—> blood —> Anterior pituitary—> ACTH—> blood —> adrenol cortex
Science   Anatomy-And-Physiology   
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Answer #1

MECHANISM OF ADRENOCORTICOTROPIC HARMONE  

Adrenocorticotropic hormone (ACTH) is secreted by the pituitary gland and reaches the adrenal cortex by blood stream.ACTH regulates the production of steroid hormones by the pitutary gland.  Two hypothalamic peptide hormones regulate  this secretion; corticotropin releasing hormone (CRH) simulates ACTH secretion synergistically with vasopressin (AVP). ACTH increase the synthesis and release of all adrenal steroids, aldosterone, Cortisol and adrenal androgens ]by acting on adrenal cortex. ACTH is secreted in a pulsatile manner with diurnal variation in its secretion .ACTH production increases in stressful conditions

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