Question

What is the purpose of the shield of negativity in the glomerulus?

		It prevents beta2 microglobulin from entering the glomerular filtrate
		It repels negatively charged molecules
		It restricts large molecules from entering glomerular filtrate
		It prevents excess electrolyte loss in the DCT

What is the normal volume of urine excreted per minute?

		1200mL/min
		600mL/min
		10mL/min
		1mL/min

Answer 1

Answer :

1) C) It repels negatively charged molecules

Explanation :the net negative charge of the GBM is a crucial component of the glomerular capillary wall's filtration barrier to plasma albumin, which is also negatively charged and should therefore be repelled by the GBM.

2) 10 mL/min

Explanation : about 1200 ml of blood is filtered through kidneys per minute but 99% of it is reabsorbed and only 1% is converted into urine per minute. Hence 1% of 1200 will be 12.