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Explain the importance of the neuro-vasculature in the normal and diseased/injured brain. Explain in clear detail.

Explain the importance of the neuro-vasculature in the normal and diseased/injured brain. Explain in clear detail.

Science   Anatomy-And-Physiology   
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Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian brain has evolved a unique mechanism for CBF control known as neurovascular coupling. This mechanism ensures a rapid increase in the rate of CBF and oxygen delivery to activated brain structures. The neurovascular unit composed of astrocytes, mural vascular smooth muscle cells and pericytes, and endothelia, regulates neurovascular coupling.

examines the cellular and molecular mechanisms within the neurovascular unit contributing to CBF control, and neurovascular dysfunction in neurodegenerative disorders such as Alzheimer's disease.

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