Question

Which of the following would be true if a medication was secreted but not reabsorbed in the kidney?

a.	There would be a higher concentration of the medicine in the renal capillaries compared to the tubular fluid
	b.	This medication is not filtered by the glomerulus
	c.	The renal clearance of this medication would be very high compared to the renal clearance of glucose
	d.	There would be a very low concentration of the medication excreted in the urine

Answer 1

Option C

Whenever the drug is only secreted but not reabsorbed, then the drug is lost in the urine in high amounts as the reabsorption is not occuring. As glucose is rapidly reabsorbed along the renal tubules, the clearance of this medication is higher when compared to the renal clearance of the glucose

The medication concentration will be high in the tubular fluid when compared to the capillaries

The drug has higher concentrations in the urine

Hope this helps... Thank you!!!