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Drug B has the following phamacokinetic parameters: Renal Clearance: 2.0L/hr Fraction Unbound in Blood: 0.8 Fraction...

Drug B has the following phamacokinetic parameters:

Renal Clearance: 2.0L/hr

Fraction Unbound in Blood: 0.8

Fraction Excreted unchanged in Urine: 1.0

Assuming a glomerular filtration rate of 7.2L/hr (for a healthy individual), which processes MUST be involved in the elimination of Drug B?

Select one:

a. Filtration and Reabsorption

b. Filtration and Secretion

c. Secretion and Metabolism

d. Filtration and Metabolism

Science   Anatomy-And-Physiology   
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