Question

1. Describe the particular locations of the T and B cells in lymph nodes.

1. Describe the particular locations of the T and B cells in lymph nodes.

Homework Answers

Answer #1
  • The outer layer (Cortex) contains the B-cell areas, or follicles.
  • The middle layer (Paracortex) is mostly populated by T cells and dendritic cells.
  • The paracortex also contains specialised blood vessels (high endothelial venules) through which many B and T cells enter the node.
  • The lymph vessels enter the nodes at the outer edge, between the capsule and the cortex, and also penetrate deep within the nodes, via conduits.
  • T and B cells leave the node via “efferent” lymphatic vessels, found in the central “medullary” region.
  • All these structures are maintained by a network of non-lymphoid cells that also actively influence immune responses.

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