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Streptomycin can damage the kidneys and the inner ear. Under what circumstances would you, as a...

Streptomycin can damage the kidneys and the inner ear. Under what circumstances would you, as a doctor, consider prescribing this medication to a patient? Explain your reasoning and use scientific data to support your claim(s).
Science   Anatomy-And-Physiology   
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Answer #1

Streptomycin is a unique antibiotic with extended antimicrobial spectrum against various bacteria, however, due to its toxicity (rashes, allergy, hearing loss) streptomycin is not used frequently.

Still, streptomycin is useful in treatment of tuberculosis. It is one of the important used in combination along with other antitubercular agents to treat multi drug resistance TB.

When given in combination with other anti TB drugs, it inhibits protein synthesis mediated by ribosomes in mycobacteria.

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