Question

Briefly describe how contraction and relaxation in smooth muscle differs from contraction and relaxation in skeletal...

Briefly describe how contraction and relaxation in smooth muscle differs from contraction and relaxation in skeletal and cardiac muscle.

Homework Answers

Answer #1
  • Unlike skeletal muscle, smooth muscle does not contain the calcium-binding protein troponin. Due to absence of troponin, cross-bridge formation is not regulated by the troponin-tropomyosin complex but instead by the regulatory protein calmodulin.
  • Unlike skeletal muscles, smooth muscles lack myofibrils.
  • Unlike skeletal muscles, smooth muscle fibres are resistant to fatigue.
  • Smooth muscles have a slower contraction speed due to
  1. Slower diffusion rate of calcium ions
  2. Rate of action potential propagation
  3. Slower cross-bridge forming.
  • Smooth muscles can contract over a wider range of resting lengths because the actin and myosin filaments in smooth muscle are not as rigidly organized as those in skeletal muscle.
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