Question

Discuss the impact of positive or negative ST-segment responses during a CPET on the posttest probability of angiographically significant CVD in subjects with different pretest probabilities (e.g., someone who is low risk vs moderate risk vs high risk for cardiovascular disease).

Answer 1

Cardiovascular Disease (CVD) are Diseases that involve the heart and/or blood vessels; includes hypertension, CAD, peripheral arterial disease; includes but not limited to atherosclerosis arterial disease.

The impact of positive or negative ST-segment responses during a CPET Prognosis and the severity of coronary artery disease and resulting ischemia during CPET is often said to be:
--Proportional to the magnitude of ST-Segment depression on ECG
--Proportional to the number of leads shown gST-Segment abnormalities on the ECG
--Proportional to the duration of ST-Segment depression into recovery
--Inversely proportional to the ST slope, the rate pressure product (RPP (HR*SBP)) at which the ST-Segment depression occurs, and the HR maximum, SBP, and metabolic equivalents achieved.