Question

Plasmapheresis is a procedure in which blood is removed, its plasma is separated from the formed elements, and the formed elements are returned to the patient or donor. Kidney transplants usually require that the donor and recipient have the same blood type. If plasmapheresis is administered to the patient before and after the transplant surgery, rejection of the kidney is less likely to occur. Explain why.

(A) Plasmapheresis removes the white blood cells, so that they do not react with the donated organ and cause a reaction.

(B)Plasmapheresis removes the red blood cells, so that they do not react with the recipient’s antibodies and cause a reaction.

(C)Plasmapheresis removes the soluble components in the blood that can trigger a rejection reaction, such as antibodies (globulins).

(D)Plasmapheresis removes the clotting factors from the blood, so they do not react with the transplant.

Answer 1

ANSWER :

Kidney transplant rejection occurs in the recipient individual occurs due to attack of white blood cells (WBCs) on the kidney. If the kidney tissue of donor don't be histocompatible with the recipient's body then immune system (cellular or T-cell mediated) of recipient individual rejects foreign tissue (antigen & proteins) and can cause various form of allergies and other disorder.

The cells of immune system (T-cells and WBCs) present in the plasma of blood and plasmapheresis process removes only plasma fluid but not RBCs (cellular component) of blood hence, statement B is least likely suitable for given condition.