Why is it important for the sisters to have similar MHC antigens?
* MHC Major HIstocompatibility Conmples is a group of genes that encode proteins on the surface that have an important role in the immune response.
* Their main role is an antigen presentation where MHC molecules display peptide fragments for the recognition of appropriate T cells.
* Its important for the sisters to have similar MHC antigens because there will not be any graft rejection since MCH is responsible for the graft rejection and it controls the graft survival.
* Hence grafts from to same genetic composition (Isograft) are not rejected whereas the grafts from different genetic composition of same species (Allograft) are rejected.
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