Question

list the events that result in the transfer of an action potential from a neuron to a skeletal muscle ( be concise and or brief with your answer and list them or number the steps)

Answer 1

Answer

Transfer of an action potential from a neuron to a skeletal muscle :

1. Arrival of action potential in the axon terminal of motor neuron.
2. Opening of voltage gated calcium channels on axon terminal (presynaptic membrane).
3. Entry of calcium ions into the axon terminal
4. Calcium ions stimulate synaptic vescicle to fuse with presynaptic membrane
5. Release of neurotransmitters from synaptic vescicles via exocytosis in to synaptic cleft.
6. Neurotransmitter (acetylcholine) binds with its receptors on postsynaptic membrane (sarcolemma of skeletal muscle fiber).
7. Opening of ligand gated sodium channels on postsynaptic membrane.
8. Influx of sodium ions into skeletal muscle fiber.
9. Depolarization of the sarcolemma and and generation of action potential in the skeletal muscle fiber.