The quantity of free calcium in the cytoplasm or cellular compartments of a cell is relatively small compared to the total amount of calcium present.
a. Where is the rest of the calcium?
b. How does the sequestered calcium impact the time of signal recovery after an induced calcium influx into the cytoplasm?
a) the major amount of the calcium is present in the bones and teeth and thus makes the human body abundant with calcium. For the bone cells to regenerate the calcium is very much issential.
b) the regulation of Ca2+ in the cell is termed as calcium homeostasis. The influx of calcium cause rise in the signal. This ca2+ is removed from the cytosol by sequestration by the mitochondria and the endoplasmic reticulum. The mitochondria remove the Ca2+ in excess and there by the removal of calcium changes the gradient and the voltage gated channel closes and the removal of the Ca2+ there by activates the opening of the Na+/K+ pump and the sodium ions moves out and the posttasium ions moves in. Now the membrane potential changes and the cell gets recovery from the impact of the signal.
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