Question

Sarah is an avid bicyclist, she decides to participate in Ragbrai 2016. On day one she bikes 40 miles. Explain how Sarah’s standard Hemoglobin-Oxygen Saturation (HOS) Curve would be affected during this intense physical activity. Does hemoglobin favor the loading or unloading of O2? What factors were affected due to exercise (i.e. how do pH, pCO2, temperature change during exercise)? Refer to the figures on Slide 2 of the poster file as you think about your response. Effect of intense physical activity on the standard Hemoglobin-Oxygen Saturation (HOS) Curve and on Oxygen loading/unloading inactively respiring tissues. Changes in pH, pCO2, temperature change during exercise.

Answer 1

Question no 1)

During intense phase of Exersice the oxy-hemoglobin dissociation curve will shift to the right side as more need for oxygen is seen that is affinity to O2 decrease

Question no 2)

Unloading of O2 is favour of hemoglobin in case of situation like Exersice as pH decrease, Carbon dioxide increse and temperature incres so unloading is favoured

Question no 3)

Factors like pH decrease will occur which favour unloading of O2 making it available to cells

Co2 increse due to Exersice and favour unloading of O2 in Hb

Temperature increases causing O2 unloading

All of these factors cause increse in affinity to O2. Decrease and favour unloading