Ischemia refers to inadequate flow of blood in arteries. The oxygen in the blood id depleted. The levels of oxygen are very less to meet the requirements of nerve tissues of the brain
Hypoxia is the decrement in the level of oxygen in the tissue which can cause a fault in production of ATP.
Ischemia and hypoxia cause abnormal autoregulation due to
(a) failure in production of energy in the neurons
(b) elevated levels of excitatory amino acids
(c) development of ischemic reperfusion injury
(d) pressure over cerebral hemodynamics
(e) adverse effect of anesthesia
(f) brain trauma injury
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