Which of the following results is most likely a result of blocking glucose uptake by liver, muscle and adipose cells?
a. all of these
b. decrease in muscle mass
c. increased beta oxidation of long-chain fatty acids in liver cells
d. increased use of amino acids in the citric acid cycle in liver cells
e. none of these
Answer is ALL OF THESE
1) decrease in muscle mass
The major source of energy for the muscle tissue is the ATP molecule. this ATPmolecules are produced as a result of cellular respiration in which the glucose is catabolized to carbon dioxide by the release of ATP molecule(oxidative phosphorylation)
So, if the glucose uptake of the muscle is blocked , there will loss of muscle tissue
2)increased beta oxidation of long chain fatty acid in the liver cells
The glucose uptake to the liver celll is blocked. so the liver will start to oxidise the long chain fatty acid for the production of energy
3) increased use of amino acids in the citric acid cycle in liver cells
Anaplerotic molecules replenishing citric acid cycle intermediates include acetyl-CoA by amino acid catabolism, α-ketoglutarate (from amino acid metabolism), and oxaloacetate from amino acid catabolism
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