Question

exlpain the chemistry of the covalent Modification (what's attached where) and the mechanism of gene silencing or gene activation

for : methylation of GPC islands by miRNA

Answer 1

First i i wi explain what miRNA is and how is gene silencing carried out

Further im explaning DNA methylation GPC island and gene silencing are related in next image

If all your doubts are cleared please do give a positive review.Thanking you.