Question

Descrive how ADH secretion during water loading changes urine production and osmolarity.

Answer 1

The antidiuretic hormone ADH stimulates water reabsorption by stimulating the insertion of "water channels" or aquaporins into the membranes of kidney collecting ducts hence allowing water reabsorption and decreasing urine production. ADH increases water and urea permeability of the distal nephron, leading to excretion of a small volume of concentrated urine, therefore minimize further loss of blood volume and decreasing the osmolarity of the plasma back toward normal levels.

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