Question

discuss the hypothalamic pituitary thyroid axis.

Answer 1

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hypothalamic pituitary thyroid axis is negative feedback control loop which helps for the regulation of metabolism in human body . Thyroid gland secretes hormones thyroxine and triiodothyronine . hypothalamus secretes thyrotropin-releasing hormone . Anterior pituitary secretes thyroid-stimulating hormone . The interaction between this hormones is the hypothalamic pituitary thyroid axis .When the level thyroid hormone reduces in the blood ,hypothalamus sense it and respond by producing thyrotropin releasing hormone . This hormone has stimulatory effect on anterior pituitary which leads to production of thyroid stimulating hormone .This hormone act on the thyroid gland to produce more thyroid hormone till the level when blood returns to normal .It’s an important pathway of direct neuro endocrine function .