Question

Select ALL That Apply

Which of the following statements would be true concerning compounds involved in calcium metabolism?

A. The most life threatening consequence of hypocalcemia is reduced blood clotting.

B. Vitamin D can be synthesized from a cholesterol derivative in the skin when exposed to sunlight.

C. PTH facilitates the activation of vitamin D which is necessary for the absorption of calcium and phosphate in the gut.

D. 1,25 dihydroxycholecalciferol is the carrier protein for calcium in the blood.

E. The most rapid response to hypocalcemia is the activation of the osteocytic membrane system by PTH.

Answer 1

A. The most life threatening consequence of hypocalcemia is reduced blood clotting.

B. Vitamin D can be synthesized from a cholesterol derivative in the skin when exposed to sunlight.

C. PTH facilitates the activation of vitamin D which is necessary for the absorption of calcium and phosphate in the gut.

Explanation: calcium ion is the most important ion responsible for the activation of various clotting factors of the coagulation pathway. Deficiency of the calcium can lead to reduced clotting.

Vit D is the hormone derived from the Cholestrol derivate synthesized from the skin which are then modified by the enzymes of the kidney by the hormone PTH.

Vit D facilitates the absorption of CA and P from the intestine.

1,25 dihydroxycholecalciferol is the active form of the Vitamine D