Question

Bacteria and viruses can enter host cells by stimulating their uptake via endocytosis. These vesicles will undergo maturation to become late endosomes, and subsequently lysosomes. Based on your knowledge of lysosomes, what changes would have to occur in the lysosome to accommodate these microbes, and how would this impact the function of the lysosome ? What advantages would this location offer for a pathogenic microbe

Answer 1

* Endosomes digest things . Viruses that escape are usually ones with not very many antibodies on it.

* The virus particle attaches to host cell. The particle releases its genetic instructions into the host cell.

* The injected genetic material recruits the hosts cells enzymes .

* The enzyme make parts for more new virus particles.

* virus and bacteria enter the membrane of the lysosome membrane and thereby digestive enzymes destroying the cell.

* The peptidoglycon layer of bacteria cell invades into lysosome and alter its function and destroying the structural function.

* If the cell is damaged or effected by bacteria or viruses beyond repair lysosomes can help it to self destruct in a process called programmed cell death or apoptosis.

* An infected cell produces more viral protein and genetic material instead of its usual products.