Question

Liver disease causes:

Question options:

a)	An increase in protein synthesis and a corresponding increase in GFR

b)	A decrease in protein synthesis and a corresponding decrease in net filtration pressure

c)	A decrease in oncotic pressure and a corresponding increase in GFR

d)	Both b and c above are correct

e)	None of the above are correct

Answer 1

Answer :  C.A decrease in oncotic pressure and a corresponding increase in GFR.

Explanation : A decrease in oncotic pressure and a corresponding increase in GFR and The Relationship between Glomerular Capillary Colloid/Oncotic Pressure and GFR

As blood passes from afferent arteriole to efferent arteriole, the plasma protein concentration increases by 20% as the plasma is being filtered. About 1/5th of plasma is being filtered into into the Bowman's capsule which leaves more protein in the capillaries, thereby increasing their concentration and thus increasing the colloid/oncotic pressure in the glomerulus as the blood moves through it, this opposes the filtration.