Question

The antibiotic Keflex is available in a solution with a concentration of 250mg per 5mL of solution or in 250-mg capsules. The recommended dosage of Keflex is 25mg/kg/day. a. How many capsules should a 40-kg person take every 6 hours. b. suppose the antibiotic solution is given intravenously to a 40kg person over a 6 hour period, using a micro drip system with a drop factor of 60gtt/ml. What drop rate should be used in units of gtt/hr.

Answer 1

a) Amount of Dosage needed by person weighing 40 kg = (25 mg/kg/day) * (40 kg) = 1000 mg/day

1 day = 24 hours

Hence we need to take every 6 hours, so the dosage will be 1/4th of the day dosage.

Amount of dosage every 6 hours = 1000 mg/day * 1 day/24 hour * 6 hour = 250 mg

Hence we need to have only one capsule of 250-mg each 6 hours

b)

1 ml = 60 drops (which is also known as drop factor)

in 1 hour, we will be needing 5 ml/24 of solution

Hence the gtt/hour will be 5 ml/24 * 60 = 12.5 gtt/hour

Therefore, drop rate should be used in gtt/hour will be equal to 12.5 gtt/hour

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