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During an experiment, you administered 10 mg of a substance to a mouse intravenously. At several...

During an experiment, you administered 10 mg of a substance to a mouse intravenously. At several intervals, you collected blood samples and analyzed them for the concentration of the chemical. You obtained the following results: 10 min, 850 mcg/ml; 30 min, 630 mcg/ml; 60 min, 395 mcg/ml; and 120 min, 160 mcg/ml. Does this elimination appear to reflect a one-compartment or two-compartment model? What is the elimination half-life? Can you calculate a volume of distribution for this chemical? If so, what is it? If not, what additional information do you need? Can you calculate a clearance for this chemical? If so, what is it? If not, what additional information do you need?

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